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TCS 4Pi

4Pi Fluorescence Microscope System

Leica 創新設計, 全世界第一套 共軛焦-4Pi 系統

帶您進入 螢光的奈米世界 !

Continuing the tradition of innovation leadership, Leica Microsystems has released the first commercial 4Pi fluorescence microscope system: Leica TCS 4PI.
   
4Pi microscopy uses a special phase- and wavefront-corrected double-objective imaging system linked to a confocal scanner to enable 4-7 fold increased axial resolution over confocal & two photon microscopy. Even in living specimens, axial sections of ~100 nm are obtained. The system maintains all advantages of fast scanning, Acousto-Optical Beam Splitting (AOBS®) and Spectral Detection of the Leica TCS SP2 AOBS for routine operation. The first marked leap in resolution in commercial 3D fluorescence microscopy opens up new dimensions for research in cell and developmental biology.

The Leica TCS 4PI system was developed in close cooperation with Prof. Stefan Hell, Head of the NanoBiophotonics Department at the Max-Planck-Institute for Biophysical Chemistry, Goettingen, Germany and was in part funded by the German Ministry of Education and Research (BMBF).

The Leica TCS 4PI system is now released as a Limited Special Edition to partnering institutions that can provide the necessary technical and application environment to optimally employ this next generation technology.

 

參考文獻 : 德國 Max-Planck 學院, Dr. Stefan W. Hell 發表的文章 ( Strategy for far-field optical imaging and writing without duffraction limit )
Leica TCS 4Pi 原廠訊息
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