徠卡顯微鏡系統
雷射掃描共軛焦顯微鏡
半導體及工業用顯微鏡
顯微數位影像系統
細胞基因影像分析系統
其它光電微機電系統
其它生醫研究儀器
維修與技術支援服務
聯絡與留言
美嘉儀器公司在原廠的獨家授權下, 結合 Andor, Roper Scientific, Hamamatsu CCD Camera 及 Leica 的顯微鏡技術, 同時, 包括顯微影像系統自動化的硬體設備, 在國內, 提供完善的技術支援與服務.
MetaMorph 高階影像處理分析軟體, 擁有全世界最大的使用客戶群. 目前最新版本為 Version 7.0. 本公司培訓多名技術專員, 多年以來, 已提供國內許多客戶相關應用. 目前, 已派員前往學習最新版本的技術與應用.

MetaMorph 享有的榮譽 :

1). 全世界學術界使用率最高評價第一的軟體

2). 全台灣學術界使用率最高評價第一的軟體

在台灣, 我們已提供服務超過一百套 MetaMorph 軟體, 包括其顯微影像自動擷取分析系統. 客戶包括全國各大學及研究單位. 在中國大陸, 目前與先鋒科技策略合作, 其所安裝的系統也是佔全中國第一的主導地位.

詳細資料, 請點選左圖

MetaMorph 型錄下載 ( PDF )
MataMorph V. 7.0 提供最新三種應用模組 Angiogenesis Application Module , Count Nuclei/ Cell Scoring Application Module for MetaMorph, Neurite Outgrowth ( 同時, 也包括更多的硬體支援功能, 例如 Yokogawa CSU 共軛焦掃描器, CARV-II 掃描器 ........... 等 )
Angiogenesis Application Module for MetaMorph
Left: original image, right: segmented images shows tubes (white) and nodes (green).
Count Nuclei/ Cell Scoring Application Module for MetaMorph
Left: original image, right: segmented images shows nuclei.
Left: original image, right: segmented images shows two different probes.

MetaMorph Premier has all the device drivers and most of the advanced processing capabilities built in (multi-dimensional imaging, fluorescence overlay, image stitching, motion analysis, and colocalization) for the researcher who wants maximum flexibility. The only option to select is the specific camera driver required. 

MetaMorph Basic has a robust set of image acquisition, processing, and analysis tools built in, and is a more affordable solution for the budget conscious researcher. Specific device drivers and the advanced analysis capabilities are optional and can be added as needed. This way, you only purchase the device drivers, camera driver, and advanced analysis capabilities you need now. You can always add on additional capabilities or device drivers later as your needs change.

Standard features in MetaMorph Premier and MetaMorph Basic include time lapse, spectral scan, and Z-series (with Z-motor driver) acquisition, image and stack processing such as Fast Fourier Transform (FFT), arithmetic operations, morphology filters, shading correction and background subtraction, 2D deconvolution, morphometry and distance measurements, and more.

MetaMorph Offline has the analysis capabilities of either MetaMorph Premier or MetaMorph Basic without external devices control. It is a very cost effective solution for the researcher who has an alternate image source or other MetaMorph systems. MetaMorph Offline's purpose is to load, process, and save images. It is very popular in multi-user facilities because it frees up the more expensive hardware acquisition systems by providing users offline analysis after acquisition.

 

MetaMorph provides many powerful automation tools to simplify experiments and increase speed and reliability, such as device controls, system automation, and journals.

Journals are similar to a macro and they record the actions of a MetaMorph user. They can be executed by other journals and can be edited.

The software includes standard interfaces for illumination, stage, and Z-motor devices, and it provides digital I/O to communicate with unique devices.

 

Journaling and device controls can:
  • Control the illumination wavelength, employing filter wheels, shutters, liquid crystal tunable filters, monochromators, or other wavelength selectors
  • Synchronize image acquisition and analysis with the opening and closing of shutters
  • Scan slides or multi-well plates with a motorized stage
  • Acquire images of a through-focus Z-series for subsequent deconvolution and 3D reconstruction
  • Control custom devices that accept commands through a serial or parallel port connection
  • Auto-focus at multiple stage positions or at specific intervals in a time lapse environment
Automated microscope controls can help you automate your system by:
  • Rotating objectives, change filter cube settings, open and close the shutter, switch the illumination lamp on or off, and change the lower and upper prism positions
  • Controlling the X, Y, and Z-axis positioning of a stage, move the stage, and store the positions for future use
  • Controlling automated stages to capture multiple locations in a sample or multiple samples, including dishes and multi-well plates
  • Using focus motors to collect Z-series or through-focal image sets
  • Acquiring images using eight different groups of settings for wavelength, intensity, and exposure duration
  • Acquiring a spectral scan in a range of excitation or emission wavelengths
  • Capturing a time lapse series of images at specified intervals and durations

Standard Features  ( with MetaMorph Premier and Basic systems) 

  • Binary and 8-, 16-, 24-, 48-bit image display and processing
  • Stack display and processing including best focus, montage, topographical surface, view orthogonal planes, and create movie
  • Over 20 morphology filters, including erode, dilate, skeletonize, outline, and segment
  • Arithmetic operations including add, subtract, multiply, divide, logical AND, OR, XOR, minimum, maximum, and average
  • Fast Fourier Transform (FFT)
  • Shading correction and background subtraction
  • Filters including sharpen, low pass, detect edges, unsharp mask, median filter, remove haze, and custom kernels
  • 2D deconvolution ( nearest neighbors and no neighbors)
  • 3D reconstruction
  • FRET
  • Auto expose from digital cameras
  • Time lapse acquisition
  • Spectral scan acquisition
  • Z-series acquisition ( with Z-motor driver )
  • Morphometry and distance measurements including area, hole area, standard area count, perimeter, centroid X and Y, Z-position, width, length and height, orientation, breadth, fiber length, fiber breadth, shape factor, elongated form factor, inner radius, outer radius, mean radius, equivalent radius, equivalent spheroid volume, equivalent prolate volume, equivalent oblate volume, equivalent sphere surface area, average, gray value, total gray value, optical integrated density (OD), integrated OD, intensity center X and Y, radial dispersion, texture difference moment, texture inverse difference moment, OD variance, OD relative low/medium or high areas, OD relative low/medium or high amounts, OD relative low/medium or high distances, and others including over 30 elliptical Fourier parameters to assist in defining shape analysis patterns
  • Color-combine and separate 24-bit or 48-bit images
  • Regions of interest tools
  • Image histogram
  • Data logging and exporting to text file or spreadsheet programs that support DDE (Dynamic Data Exchange) such as Microsoft® Excel
  • Automation through journals and taskbars
  • Customizable toolbars and windows
  • Presentation features including organize and label with text, date, time, or calibration bars, convert color images to monochrome, produce intensity profile images, create image montages and movies, overlay images, and document the operations performed on the images

Microscope Control Options ( 顯微鏡自動化控制功能 )

  • Most popular automated microscope models from Leica, Nikon, Olympus, and Zeiss
  • Digital auto-focus
  • XY stage device control for popular models from major manufacturers
  • Z-axis device control for popular models from major manufacturers
  • Piezo-actuated Z and XY device control
  • Monochromator control for illumination
  • Filter wheel and shutter control
  • UniBlitz® shutters
  • AOTF for laser control
  • Liquid Crystal tunable filters
  • Custom I/O (RS-232 serial and TTL parallel)

Acquisition Options ( 影像擷取控制選配 )

  • Digital CCD cameras, both monochrome and color, including: cooled, full frame, frame transfer, interline, back thinned, intensified, and on-chip multiplication gain, from major manufacturers
  • Video cameras, both monochrome and color, including: RS-170, CCIR, on-chip integration, intensified, CCD, and tube, from major manufacturers
  • Simultaneous acquisition from two cameras or control of an image splitting device for projection of two or four emission wavelengths onto a single camera (appropriate hardware required)
  • Wavelength streaming and/or Z-axis streaming ( 專利設計 )

Optional Features for Basic Systems  ( MetaMorph Premier systems 包括此部分軟體功能 )

  • Multi-dimensional imaging
  • Overlay multi-fluorescent images
  • Image stitching
  • Motion analysis and particle tracking
  • Colocalization and correlation measurements

Additional Modules ( 選配軟體模組 )

  • 3D deconvolution
  • Advanced 3D visualization
  • Neurite outgrowth
一些主要應用包括 :

 

可被 MetaMorph 控制的基本硬體表
AOTF Prairie Technologies, LLC. Find out more
Axio Imager.Z1 Zeiss Find out more
Axio Observer.Z1 Zeiss Find out more
Axioplan 2 (MTB) Zeiss Find out more
Axioplan 2 Imaging (MTB) Zeiss Find out more
Axioskop 2 MOT (MTB) Zeiss Find out more
Axiovert 100 M (MTB) Zeiss Find out more
Axiovert 200 M Zeiss Find out more
BioPoint Ludl Find out more
C2400 Hamamatsu Find out more
C4880-10 Hamamatsu Find out more
C4880-21 Hamamatsu Find out more
C4880-80 Hamamatsu Find out more
C4880-81 Hamamatsu Find out more
C6790 (HISCA) Hamamatsu Find out more
C7190-2x Hamamatsu Find out more
C7300-51-12 NRB Hamamatsu Find out more
C9100-02 Hamamatsu Find out more
C9100-12 Hamamatsu Find out more
C9100-13 Hamamatsu Find out more
CARV II Confocal Imager BD Biosciences Find out more
Cascade 128 Photometrics Find out more
Cascade 1K Photometrics Find out more
Cascade 512B Photometrics Find out more
Cascade 512F Photometrics Find out more
Cascade 650 Photometrics Find out more
Cascade II: 512 Photometrics Find out more
Cell Robotics Stage Cell Robotics International, Inc. Find out more
CIO-DAC02 Measurement Computing Find out more
Computerized Z Motor Conix Research Find out more
CoolSNAP Photometrics Find out more
CoolSNAP cf Photometrics Find out more
CoolSNAP ES Photometrics Find out more
CoolSNAP ES2 Photometrics Find out more
CoolSNAP EZ Photometrics Find out more
CoolSNAP FX Photometrics Find out more
CoolSNAP HQ Photometrics Find out more
CoolSNAP HQ2 Photometrics Find out more
CoolSNAP K4 Photometrics Find out more
CORVUS Marzhauser Find out more
CSU-21 Yokogawa Find out more
CSU-22 Yokogawa Find out more
DaqBoard 2000 IOTech Find out more
DaqBoard 2001 IOTech Find out more
DCAM Hamamatsu Find out more
DeltaRAM Photon Technology International Find out more
Discovery-1 Universal Imaging Corporation Find out more
DM4000 Leica Microsystems Find out more
DM4500 Leica Microsystems Find out more
DM5000 Leica Microsystems Find out more
DM6000 Leica Microsystems Find out more
DM6000 with MIC 6500 Leica Microsystems Find out more
DMI6000-B Leica Microsystems Find out more
Dual-Cam Optical Insights Find out more
Dual-View Optical Insights Find out more
DXM-1200 Nikon Instruments Find out more
DXM-1200c Nikon Instruments Find out more
DXM-1200f Nikon Instruments Find out more
E710 Physik Instrumente Find out more
Eclipse i-Series 90i Nikon Instruments Find out more
Flashbus MV-Pro Integral Technologies Find out more
FluoroSpec Cambridge Research & Inst. (CRI) Find out more
FW-1000 High Speed Filter Wheel Applied Scientific Instrumentation Find out more
Gen II Multi Dimensional Imager Universal Imaging Corporation Find out more
HEXFILT Conix Research Find out more
I Pentamax III Princeton Instruments Find out more
Insight 3-Shot Color Diagnostic Instruments Find out more
Insight Color Mosaic Diagnostic Instruments Find out more
Insight Firewire 3-Shot Color Diagnostic Instruments Find out more
Insight Firewire Color Mosaic Diagnostic Instruments Find out more
Insight Firewire Monochrome Diagnostic Instruments Find out more
Insight Monochrome Diagnostic Instruments Find out more
Insight QE 3-Shot Color Diagnostic Instruments Find out more
Insight QE Color Mosaic Diagnostic Instruments Find out more
Insight QE Monochrome Diagnostic Instruments Find out more
iXon DU 897-BV Andor Technology Find out more
iXon DU-860 Andor Technology Find out more
iXon DU-885 Andor Technology Find out more
iXon DU-888 Andor Technology Find out more
iXon DV 887-BV Andor Technology Find out more
iXon DV 887-FI Andor Technology Find out more
iXon DV 897-BV Andor Technology Find out more
iXon DV-885 Andor Technology Find out more
Lambda 10 Sutter Instruments Find out more
Lambda 10-2 Sutter Instruments Find out more
Lambda 10-3 USB w/ Smart Shutter Sutter Instruments Find out more
Lambda 10-B Sutter Instruments Find out more
Lambda 10-B w/ Smart Shutter Sutter Instruments Find out more
Lambda 10-C Sutter Instruments Find out more
Lambda DG-4 Sutter Instruments Find out more
Lambda DG-5 Sutter Instruments Find out more
Lambda SC USB w/ Smart Shutter Sutter Instruments Find out more
Leica DM IRB Leica Microsystems Find out more
Leica DM IRBE Leica Microsystems Find out more
Leica DM IRE2 Leica Microsystems Find out more
Leica DM LA Leica Microsystems Find out more
Leica DM LB Leica Microsystems Find out more
Leica DM LFS Leica Microsystems Find out more